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Neuroscience

Dedicated to the art and science of neuroscience clinical research

With an approval rate for neuroscience therapies that is about half that for other drugs, the distinct challenges of clinical research in this area – accelerating recruitment, measuring highly subjective endpoints, countering placebo effects, demonstrating meaningful clinical efficacy – need to be met with an uncommon blend of scientific depth and elegant problem-solving.

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Read our perspectives on the latest trends in neuroscience clinical research.

With dedicated experts and teams focused on areas like psychiatry, Alzheimer's and more, we are structured to meet the complexity of your CNS research with uncommon experience and insight.

Expertise and resilience, when and where it counts

No other area of medical research requires as much precision and inventiveness to achieve meaningful outcomes.

With over 3,500 highly experienced global industry-leading neuroscience experts, including licensed clinicians, medical monitors, clinical leads, as well as project management and delivery team members, we are committed to helping you overcome the challenges inherent in neuroscience research, offering you:

Scientific and Strategic Therapeutic Excellence

  • In-depth, industry-leading clinical and therapeutic expertise in neuroscience for scientifically driven study strategy and protocol design, including rare disease, cell and gene therapy and pediatrics
  • Clinical development experts with extensive operational backgrounds who are therapeutically focused on the initial planning of the study and providing continuous steadfast support
Operational Leadership

  • Full Service. Proficiency in project delivery for multi-service and full-service studies through all phases from clinical development through commercialization
  • Positive Outcomes. Proven track record for studies and programs, including 56 positive neuroscience studies that enrolled during the COVID-19 pandemic (March 2020 - 2022), for which we provided full service
Clinical Surveillance and Training (CST)

  • Dedicated in-house team of endpoint integrity experts including licensed clinical psychologists, neuropsychologists and psychiatrists, with scientific and therapeutic expertise
  • Optimization of signal detection for subject protection and the overall study investment for at-risk trials with subjective outcomes

Experienced in a wide range of neuroscience disorders including:

Neurology

From recruiting the right patients, to ensuring assessments are completed properly by trained experts and that all stakeholders are aligned, we have managed these complexities and more across a range of challenging neurological study design and difficult-to-recruit indications across neurology including:

• Cerebrovascular
• Neurodegenerative (including Alzheimer’s disease clinical trials )
• Movement
• Neurodevelopmental
• Neuromuscular
• Seizure
• Sleep

Psychiatry

The success of your psychiatry clinical trial hinges on precision in study design, site selection, subject recruitment, the quality and evaluation of raters and the monitoring and delivery of high-quality data. Our experts in psychiatry research offer deep scientific and clinical experience for studies of:

• Mood (including depression, post-partum depression and major depressive disorder clinical trials)
• Anxiety
• Psychosis (including schizophrenia clinical trials)
• Trauma
• Developmental
• Substance abuse
Psychotherapeutics (including Psychedelics clinical trials)

Analgesia

We have an established reputation for our work in pain management, including the design, feasibility, execution, analysis and interpretation of studies in a variety of acute, sub-acute and chronic pain disorders, rare indications and pediatric pain, including:

  • Chronic low back pain
  • Migraine
  • Neuropathic pain
  • Osteoarthritis
  • Post-surgical pain

Ophthalmology

Ophthalmology clinical trials are highly specialized. Our Ophthalmology team consists of more than 360 ophthalmology-trained staff, including eleven board-certified ophthalmologists in North America, Europe and Asia Pacific who are experts in the field and dedicated to vision research with biosimilar, cell & gene therapy and device therapies in areas that include:

  • Cornea
  • Eyelid
  • Glaucoma
  • Inherited retinal
  • Ocular inflammation
  • Optic nerve
  • Refractive
  • Retina

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